RAPAMYCIN-INSENSITIVE MTORC1 ACTIVITY CONTROLS EIF4E:4E-BP1 BINDING [V1; REF STATUS: INDEXED, HTTP://F1000R.ES/NM6HPO]

Rapamycin-insensitive mTORC1 activity controls eIF4E:4E-BP1 binding [v1; ref status: indexed, http://f1000r.es/NM6hpo]

The recent development of mammalian target of rapamycin (mTOR) kinase domain inhibitors and genetic dissection of rapamycin-sensitive and -insensitive mTOR protein complexes (mTORC1 and mTORC2) have revealed that phosphorylation of the mTOR Office Chair substrate 4E-BP1 on amino acids Thr37 and/or Thr46 represents a rapamycin-insensitive activity o

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Proficiat Jef

Proficiat Jef.Proficiat Jef On 2 July 2015, emeritus celebrations Electrical Parts were held in honour of Professor Jozef Vercruysse at the University of Ghent.His special relationship with Tropicultura, together with the scope and quality of all that he has accomplished during his professional life in the field of parasitology, which plays a parti

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High-level expression of Bacillus naganoensis pullulanase from recombinant Escherichia coli with auto-induction: effect of lac operator.

Pullulanase plays an important role in specific hydrolysis of branch points in amylopectin and is generally employed as an important enzyme in starch-processing industry.So far, however, the production level of pullulanase is still somewhat low from wide-type strains and even heterologous expression systems.Here the gene encoding Bacillus naganoens

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Ceftolozane-Tazobactam Treatment of Hypervirulent Multidrug Resistant Pseudomonas aeruginosa Infections in Neutropenic Patients

The effectiveness of ceftolozane/tazobactam New Pressure Washer for the treatment of infections in neutropenic patients caused by hypervirulent multidrug-resistant (MDR) Pseudomonas aeruginosa has not been previously reported.We identified seven cases of MDR P.aeruginosa infection in neutropenic patients over a four-month period within the same hem

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